Dr Niyaz Ahmed, Senior Director, icddr,b

Look at the sky. We are not alone. The whole universe is friendly to us and conspires only to give the best to those who dream and work – APJ Abdul Kalam, former President of India (2002-07)

DSC_0673Niyaz Ahmed (Researcher ID D-2589-2010) is a Senior Director at the International Centre for Diarrheal Disease Research (icddr, b). A Fellow of the American Academy of Microbiology, the Royal Society of Chemistry (UK), the Royal Society of Biology (UK) and the National Academy of Sciences India, as well as the founder Editor -in-Chief of Gut Pathogens journal, Dr Ahmed is also the recipient of the ‘Shanti Swarup Bhatnagar Prize’, India’s top most Science Prize, for the year 2016 in the area of Medical Sciences.  In 2017, Dr Ahmed was awarded the Microsoft Azure for Research Award in Public Health to work towards genomics of identification of new genes, new proteins and novel pathways underlying the multiple drug resistance phenotypes in bacteria.

47-0.jpgDr Ahmed is the third Indian national to be appointed as Senior Director of icddr,b after V. I. Mathan and G. Balakrish Nair who earlier served as Associate Directors.

Dr Ahmed also holds appointment as Adjunct Professor of the Academy of Scientific and Innovative Research, India and Professor at the University of Hyderabad (on leave). He is a Corresponding Fellow of the European Helicobacter and Microbiota Study Group.

Through his pioneering and translational work in public health microbiology in India, Ahmed recorded founding efforts to the development of Molecular Epidemiology of bacterial pathogens in this country and  made seminal contributions to host-pathogen epidemiology of bacterial pathogens such as TB bacilli and Helicobacters (Ahmed et al., 2008, Nature Reviews Microbiol.), and also in unraveling the population genetic structure and virulence mechanisms of major human pathogens: H. pylori,  M. tuberculosis, E. coli and S. enterica.

Dr Ahmed’s contributions strengthened molecular basis of survival of pathogens in single patients and in host communities with varied genetic backgrounds (Kumar/Ahmed, 2015 Nucleic Acids Res; Baddam/Ahmed 2014, Scientific Reports).

Kalam1

Dr Ahmed was inspired by the People’s President, Dr APJ Abdul Kalam

Niyaz Ahmed serves on the Editorial Boards of the following international journals: Scientific Reports (Nature), Helicobacter (Wiley), Systems and Synthetic Biology (Elsevier), Infectious Agents and Cancer (Springer), Microbial Genomics (SGM, UK), Journal of Health & Translational Medicine (University of Malaya Medical Centre), Emerging Microbes and Infections (Nature), PLOS ONE (PLOS journals) and F1000 Research (F1000, UK).

Important publications of Dr Ahmed and teams:

(Access here all publications of Dr Ahmed through pubMED)

Islam MA, Roy S, Nabi A, Solaiman S, Rahman M, Huq M, Siddiquee NA, Ahmed N. Microbiological quality assessment of milk at different stages of the dairy value chain in a developing country setting. Int J Food Microbiol. 2018 Aug 2;278:11-19.

Shaik S, Ranjan A, Tiwari SK, Hussain A, Nandanwar N, Kumar N, Jadhav S, Semmler T, Baddam R, Islam MA, Alam M, Wieler LH, Watanabe H, Ahmed N. Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages. MBio. 2017 Oct 24;8(5).

Ranjan A, Shaik S, Nandanwar N, Hussain A, Tiwari SK, Semmler T, Jadhav S, Wieler LH, Alam M, Colwell RR, Ahmed N. Comparative Genomics of Escherichia coli  Isolated from Skin and Soft Tissue and Other Extraintestinal Infections. MBio. 2017 Aug 15;8(4).

Doddam SN, Peddireddy V, Ahmed N. Mycobacterium tuberculosis DosR Regulon Gene Rv2004c Encodes a Novel Antigen with Pro-inflammatory Functions and Potential Diagnostic Application for Detection of Latent Tuberculosis. Front Immunol. 2017 Jun 24;8:712.

Peddireddy V, Doddam SN, Ahmed N. Mycobacterial Dormancy Systems and Host Responses in Tuberculosis. Front Immunol. 2017 Feb 15;8:84

Qumar S, Majid M, Kumar N, Tiwari SK, Semmler T, Devi S, Baddam R, Hussain A, Shaik S, Ahmed N. Genome dynamics and molecular infection epidemiology of multi-drug resistant Helicobacter pullorum isolates obtained from broiler and country chickens in India. Appl Environ Microbiol. 2016 Dec 15;83.

Devi S, Ansari SA, Tenguria S, Kumar N, Ahmed N. Multipronged regulatory functions of a novel endonuclease (TieA) from Helicobacter pylori. Nucleic Acids Res. Nov 2;44(19):9393-9412.

Ranjan A, Shaik S, Mondal A, Nandanwar N, Hussain A, Semmler T, Kumar N, Tiwari S, Jadhav S, Wieler LH, Ahmed N. Molecular epidemiology and genome dynamics of New Delhi metallo-beta-lactamase (NDM) producing extraintestinal pathogenic E. coli (ExPEC) strains from India. Antimicrob Agents Chemother. Oct 21;60(11):6795-6805.

Ranjan A, Shaik S, Hussain A, Nandanwar N, Semmler T, Jadhav S, Wieler LH, Ahmed N. Genomic and functional portrait of a highly virulent, CTX-M-15-producing H30-Rx subclone of Escherichia coli sequence type (ST) 131. Antimicrob Agents Chemother. 2015, 59:6087-95.

Kumar N, Mariappan V, Baddam R, Lankapalli AK, Shaik S, Goh KL, Loke MF, Perkins T, Benghezal M, Hasnain SE, Vadivelu J, Marshall BJ, Ahmed N. Comparative genomic analysis of Helicobacter pylori from Malaysia identifies three distinct lineages suggestive of differential evolution. Nucleic Acids Res. 2015 Jan;43(1):324-35.

Baddam R, Kumar N, Shaik S, Lankapalli AK, Ahmed N. Genome dynamics and evolution of Salmonella Typhi strains from the typhoid-endemic zones. Scientific Rep 2014 Dec 12;4:7457.

Hussain A, Ranjan A, Nandanwar N, Babbar A, Jadhav S, Ahmed N. Genotypic and phenotypic profiles of Escherichia coli isolates belonging to clinical sequence type 131 (ST131), clinical non-ST131, and fecal non-ST131 lineages from India. Antimicrob Agents Chemother. 2014, 58:7240-9.

Hussain A, Ewers C, Nandanwar N, Guenther S, Jadhav S, Wieler LH, Ahmed N. Multiresistant uropathogenic Escherichia coli from a region in India where urinary tract infections are endemic: genotypic and phenotypic characteristics of sequence type 131 isolates of the CTX-M-15 extended-spectrum-β-lactamase-producing lineage. Antimicrob Agents Chemother. 2012, 56:6358-65.

Ahmed N, Dobrindt U, Hacker J, Hasnain SE. Genomic fluidity and pathogenic bacteria: applications in diagnostics, epidemiology and intervention. Nat Rev Microbiol. 2008 6:387-94.

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